Personalized diagnostic and therapeutic solutions for patients
Study group Primary and secondary brain tumors in adults
Prospective (BZKF-AYA study) and retrospective (BZKF-PHT-01 study) collection of clinical data, imaging data and biomaterials to investigate treatment response and resistance as well as molecular target structures in patients with primary brain tumors.
Patients with brain tumors often have an unfavorable prognosis. In this study, we want to use clinical data, imaging data and biomaterials to improve diagnostics, more precise parameters for response and resistance, insights into the genetic evolution of brain tumors and molecularly guided personalized therapies.
To the press release "BZKF-AYA study: research for the future"
Personalized therapy management for primary brain tumors has not yet been established across the board. One reason for this is the frequent lack of availability of less invasive and longitudinally acquired clinical and imaging data as well as biomaterial and the lack of standardization of MR and PET imaging as biomarkers for the analysis of response and resistance and the selection of targeted therapies in these patients. Therefore, we are conducting a prospective (BZKF-AYA) and retrospective (BZKF-PHT-01) non-interventional biomarker study.
- Clinical data, imaging data and biomaterials from patients with primary brain tumors are to be recorded and processed uniformly throughout Bavaria
- Imaging data and biomarkers should enable longitudinal, minimally invasive and maximally individualized management of patients with primary brain tumors
- Insights into therapy response and resistance, genetic evolution and molecular target structures for personalized therapies should be accessible to all patients with primary brain tumors in Bavaria in the medium term
Further study groups
- Acute myeloid leukemia (AML)
- Cancer of Unknown Primary (CUP)
- Endocrine and neuroendocrine tumors
- Head and neck tumors
- Liver carcinoma
- Lung tumors
- Lymphoma
- Malignant melanoma
- Multiple myeloma
- Breast cancer
- Ovarian carcinoma
- Prostate carcinoma
- R/R ALL
- Urothelial carcinoma
- Soft tissue sarcomas
- CNS tumors in children and adolescents
