Cooperation between ENT, radiation oncology and OMFS

Head and neck tumor study group

  • Bavaria-wide uniform tumor documentation for register formation
  • Future-oriented hypothesis generation (think tank)
  • Collection of material for polycentric biomarker-driven studies

Head and neck oncology arises in a highly complex anatomical region that requires interdisciplinary therapeutic approaches. The most common tumours in this region are also characterized by great molecular-biological heterogeneity. These two prerequisites have led to divergent aspects in the assessment of therapy and success. This makes it difficult and prone to error to evaluate the results of therapy and clinical research. The SG pursues 3 consecutive goals:

  • Common database (register)
  • Hypothesis generation
  • Clinical studies

To this end, the SG is forming three working groups that will work on the objectives in parallel. The results of the working groups converge in a joint polycentric biomarker-driven research proposal that utilizes the outstanding expertise of the individual sites.

 


The milestones for the three WGs are defined for 3, 6, 9 and 12 months:

 

WG Documentation:

3 M: Definition of the documentation areas (e.g. molecular, clinical)

6 M: Interim evaluation of the items

9 M: Condensation of the parameters into one data set

12 M: Finalization (SG) in the SG

 

WG material and structure:

3 M: Analysis of local structures (e.g. material collections, biobanking)

6 M: Development of SOPs for material collection

9 M: Study project proposals (together with hypotheses working group) with proposal preparation (e.g. ethics)

12 M: Joint research proposal (SG)

 

AG Hypotheses and projects:

3 M: Identification of promising fields of research

6 M: Differentiation between short- and long-term project ideas

9 M: Support of the Material and Structure WG for the biomarker application

12 M: Prospective applications (SG)

  • Joint data set and register
  • Further applications (hypotheses) based on the first biomarker research application
  • External third-party funding
  • Outcome studies on a registry basis
  • Definition of best practice and thus outreach
  • Joint study centers for industrial partners

BZKF Study Group Head and Neck Tumors